Few regions in Belgium bring together as much knowledge within such a small radius as Leuven. KU Leuven, imec, UZ Leuven, VIB and EnergyVille are all located within a few kilometres of one another. The imec cluster alone accounts for more than 13,400 jobs, including 2,900 in spin-offs. Since 1972, KU Leuven has created 199 spin-offs of its own, ten of them in 2025, together accounting for more than 7,700 jobs. There is no shortage of research or innovative ideas. The real challenge is turning those ideas into businesses that can grow sustainably. A spin-off that invests in research for years before generating its first revenue has very different financial needs from an established SME. And when a company suddenly begins attracting international clients, questions around structure, IP protection or cybersecurity can arise sooner than expected.





